Venous Thromboembolism (VTE): A Hidden and Dangerous "Silent Killer"
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a disease with a high incidence and potential lethality. Due to its often atypical clinical manifestations, early and accurate diagnosis is crucial for timely treatment and improved prognosis. D-dimer is a product of thrombus formation and fibrinolysis in the body. Its detection, especially high-sensitivity D-dimer (hs-D-dimer) detection, plays a central role in the exclusion diagnosis of VTE, effectively helping clinicians identify low-risk patients and avoid unnecessary, expensive, and potentially risky imaging examinations.
Advantages of reOpenTest High-Sensitivity D-dimer Detection
High Negative Predictive Value (NPV)
For suspected VTE patients with low to moderate clinical probability assessment, a negative result of high-sensitivity D-dimer detection has an extremely high NPV, which can safely exclude VTE diagnosis.
Reduce Unnecessary Imaging Examinations
By effectively excluding VTE, the need for examinations such as vascular ultrasound and CT pulmonary angiography (CTPA) can be significantly reduced, lowering medical costs and patient radiation exposure.
Rapid and Convenient POCT
Point-of-care testing (POCT) design, can provide results in 15-20 minutes, especially suitable for rapid decision-making in the emergency department and outpatient clinics.
Optimize the Allocation of Medical Resources
Rapidly exclude low-risk patients so that medical resources can be more focused on further diagnosis and treatment of high-risk or confirmed patients.
Clinical Application and Guidelines Recommendations
reOpenTest high-sensitivity D-dimer rapid test is mainly used for:
- Exclusion diagnosis of suspected deep vein thrombosis (DVT) patients.
- Exclusion diagnosis of suspected pulmonary embolism (PE) patients.
- Develop VTE diagnostic strategies in combination with clinical probability scores (such as Wells score, Geneva score).
- In some cases, it can also be used for the auxiliary diagnosis and monitoring of disseminated intravascular coagulation (DIC).
Multiple European and international clinical guidelines recommend that VTE of low to moderate clinical risk can be safely excluded when high-sensitivity D-dimer detection is negative. Our products are designed to meet the testing performance requirements of these guidelines.
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Learn more about reOpenTest high-sensitivity D-dimer rapid test products and their application details in VTE exclusion diagnosis.
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